The September 2007 Vanity Fair features an article by Suzanna Andrews about playwrite Arthur Miller and his son Daniel, who was born with Down syndrome. Shortly after birth, Miller placed Daniel in an institution, and never made contact again. The article suggests several reasons for Miller’s actions, including the fear that raising Daniel would distract him from his work.
As a counterpoint, I offer Pearl S. Buck: Pulitzer Prize for the novel (1932), Nobel Prize for Literature (1938), author of more than 70 published works, and mother to six children including Carol, a multiply-disabled daughter with the then-undiagnosed condition PKU.
And a quote from Pearl S. Buck, here:
In a mood of faith and hope my work goes on. A ream of fresh paper lies on my desk waiting for the next book. I am a writer and I take up my pen to write.